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Evidence-Based Practice: Home

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What is Evidence Based Practice?

Dr. David Sackett

Nov. 17, 1934 - May 13, 2015


"Evidence-Based Medicine is the integration of best research evidence with clinical expertise and patient values."

(Dr. David Sackett et al., 2000) 

Best Research Evidence: Clinically relevant research conducted using sound methodology from the basic sciences of medicine and patient  centered clinical research. (Sackett et al., 2000)

Clinical Expertise: The combination of the basic skills of clinical practice, individual clinical experience, and education to determine the applicability of  external evidence to the patient's particular clinical state and circumstances. (Sackett et al., 2000; Haynes, et al., 2002)

Patient Values: The unique preferences, concerns and expectations the patient brings to the clinical encounter. (Sackett et al., 2000)  
Venn-Diagram developed using LucidChart 

Evidence-Based Practice: A Five Step Process

  1. Ask a focused and well-articulated question that is relevant to the patient's clinical problem.

  2. Acquire clinically relevant evidence from appropriate resources.

  3. Appraise the evidence for validity and applicability.

  4. Apply critically appraised evidence (along with clinical expertise and the patient's preferences and unique clinical circumstances) to patient care.

  5. Assess the effectiveness of the process and performance of the evidence in clinical application.



JAMAevidence provides fundamental tools for understanding and applying the medical literature and making clinical diagnoses. Take a tour of the site below:

theNNT (New!)

theNNT provides a framework and rating system to evaluate therapies based on their patient-important benefits and harms as well as a system to evaluate diagnostics by patient sign, symptom, lab test or study.
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